The Alcohol and Other Drug Thesaurus:

A Guide to Concepts and Terminology in Substance Abuse and Addiction

Volume 1: Introduction and Overview

Volume 2: Annotated Hierarchy

Volume 3: Alphabetical Index

Volume 4: Annotated Alphabetical List

Developed jointly by the

National Institute on Alcohol Center for Substance
Abuse and AlcoholismAbuse Prevention
National InstitutesSubstance Abuse and Mental
of HealthHealth Services Administration

Public Health Service

U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

Second Edition
October 1995

Sponsoring Agencies

National Institute on Alcohol
Abuse and Alcoholism

Enoch Gordis, M.D., Director
Diane W. Miller, M.P.A., Chief,
Scientific Communications Branch
Alcohol Research Collection, Analysis,
and Dissemination Project

Center for Substance Abuse Prevention

Elaine M. Johnson, Ph.D., Director
Nelia C. Nadal, M.P.H.,
Division of Publication Education
and Dissemination
Center for Substance Abuse Prevention
Project Officer, NCADI

Thesaurus Development Team

CSR, Incorporated
1400 Eye St., N.W., Suite 200
Washington, DC 20005

Dianne M. Welsh, Director
Contract NO1-AA-10001

SHS, Ltd.
11426-28 Rockville Pike
Rockville, MD 20852

Roe Wilson, Deputy Director
Contract 277-90-4010

Dagobert Soergel, Ph.D.,
Thesaurus Expert

Kathleen A.K. Mullen, M.L.I.S.,
Thesaurus Manager

Colleen Auth,
Lexicographer

Order from NCADI,
P.O. Box 2345,
Rockville, MD 208-2345,
1-800-729-6686

Preface

The Alcohol and Other Drug Thesaurus: A Guide to Concepts and Terminology in Substance Abuse and Addiction was developed under the auspices of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the Center for Substance Abuse Prevention (CSAP) to record and systematize the language of the many scientific and scholarly disciplines relating to research on alcohol and other drugs and the prevention and treatment of problems associated with their use. A subset of the Thesaurus also serves as the controlled vocabulary for the Alcohol and Alcohol Problems Science Database (commonly known as ETOH), produced by NIAAA, and the numerous information systems of CSAP's National Clearinghouse for Alcohol and Drug Information.

Enoch Gordis, M.D.
Director
National Institute on Alcohol
Abuse and Alcoholism
National Institutes of Health
Elaine M. Johnson, Ph.D.
Director
Center for Substance Abuse Prevention
Substance Abuse and Mental Health
Services Administration

Acknowledgments

The National Institute on Alcohol Abuse and Alcoholism and the Center for Substance Abuse Prevention would like to acknowledge the efforts of the numerous people who contributed to the development of The Alcohol and Other Drug Thesaurus: A Guide to Concepts and Terminology in Substance Abuse and Addiction over the past several years. We would like to acknowledge in particular the efforts and significant contributions of Barbara Thomas, who served as the thesaurus manager on behalf of CSR, Incorporated, from February 1990 through December 1991, and James R. Wheatley, who served as the lexicographer from February 1992 through December 1993. We also would like to acknowledge the contributions of Terry Freeman, Susan Labin, Cate Timmerman, and Andy Katz, as well as the many staff members who supported and participated in the development of the Thesaurus.

We would like especially to thank the many scientists, technical experts, researchers, and subject specialists who contributed their time and knowledge to the development of this Thesaurus.

We also would like to thank the following institutions for their participation in the testing phase of the Thesaurus: ALKO, Ltd., Helsinki, Finland; Addiction Research Foundation, Toronto, Ontario, Canada; British Columbia Prevention Resource Center, Vancouver, British Columbia, Canada; Alcohol Research Group, Berkeley, California; Distilled Spirits Council of the U.S., Washington, D.C.; Drug Information Services, Minneapolis, Minnesota; Marin Institute, San Rafael, California; Research Institute on Addictions, Buffalo, New York; Rutgers University Center on Alcohol Studies, Piscataway, New Jersey; and the Veterans Affairs Medical Center, Grand Junction, Colorado.

Thesaurus Advisory Committee

Dagobert Soergel, Ph.D., Chair
Professor, College of Library
and Information Services
University of Maryland
College Park, MD 20742-4345

Leigh Hallingby, M.L.S.
Librarian, The Lindesmith Center
888 Seventh Avenue
New York, NY 10106

Samantha Helfert, M.L.I.S
Librarian, National Center
for the Advancement of
Prevention
11140 Rockville Pike, Suite 600
Rockville, MD 20852

Diane W. Miller, M.P.A.
Chief, Scientific Communications Branch
Office of Scientific Affairs
NIAAA
6000 Executive Boulevard, Suite 409
Bethesda, MD 20892-7003

Andrea Mitchell, M.L.S.
Director/Librarian, Alcohol
Research Group Library
2000 Hearst Avenue, 3rd Floor
Berkeley, CA 94709

Nelia C. Nadal, M.P.H.
Division of Publication Education
and Dissemination
Center for Substance Abuse Prevention
Project Officer, NCADI
5600 Fishers Lane
Rockville, MD 20857

Penny Page, M.L.S.
Library Director, Rutgers Univ.
Center on Alcohol Studies
Smithers Hall, Busch Campus
Piscataway, NJ 08854

Virginia Rolett, M.L.S.
ISU, Inc.
4 Balch Hill Lane
Hanover, NH 03755

Alicia Spinak
CICAD-IADI
1889 F Street, N.W.
Washington, D.C. 20006

Nancy Sutherland, M.L.S.
Library Director
Alcohol & Drug Abuse Institute Library
3937 15th Avenue, N.E., NL-15
Seattle, WA 98105

Gail Weinberg, M.L.S.
Librarian, Drug Information Services
University of Minnesota Hospital
420 Delaware Street, S.E.
Minneapolis, MN 55455

Consultant Subject Experts

Thomas Babor, Ph.D., M.P.H.
Department of Psychiatry
School of Medicine, University of Connecticut
Farmington, CT 06032

James C. Beck, M.D., Ph.D.
The Commonwealth of Massachusetts
Cambridge Division
District Court, Department of the Trial Court
Court Clinic
Cambridge, MA 02141

William DeJong
Lecturer, Harvard School of Public Health
29 Rice Spring Lane
Wayland, MA 02141

Richard A. Dietrich, M.D.
Department of Pharmacology
Health Science Center, University of Colorado
Denver, CO 80262

Robert Huebner, Ph.D.
Health Services Research Program
NIAAA
6000 Executive Boulevard, Suite 505
Bethesda, MD 20892-7003

Michael Lewis, Ph.D.
Professor, Psychology Department
Temple University
Weiss Hall 657
13th Street and Cecil B. Moore Avenue
Philadelphia, PA 91922

Raye Z. Litten Ph.D.
Treatment Research Branch
NIAAA
6000 Executive Boulevard, Suite 505
Bethesda, MD 20892-7003

Cesar Romero-Sierra, M.D.
Neuroanatomy Section
Department of Anatomy
Queen's University
Kingston, Canada K7L 3N6

Marcus A. Rothschild, M.D.
Nuclear Medicine Service
Veterans Affairs Medical Center
New York, NY 10010

Alvera Stern, Ed.D.
409 Shelburne Drive
Carol Stream, IL 60188

Elva Yaez, M.S.L.S.
California Latino Coalition
on Alcohol and Other Drugs
521 Talbot Avenue
Albany, CA 94706-2303

History and Purpose of the Alcohol and Other Drug Thesaurus

Research in the alcohol and other drugs (AOD) field and programs in prevention and treatment have grown significantly over the last 20 years; so have the literature and the information needs of users and the collections and databases serving them. This growth has occurred without the benefit of a stable, consistent vocabulary, making storage and retrieval of materials difficult. Responding to a recommendation from SALIS (Substance Abuse Librarians and Information Specialists) for a thesaurus for the AOD field, the National Institute on Alcohol Abuse and Alcoholism (NIAAA) undertook the task of developing an alcohol thesaurus for the field in general and its online database, the Alcohol and Alcohol Problems Science Database (known as ETOH). In 1989 NIAAA formed a Thesaurus Advisory Committee of information and subject specialists. In 1991, recognizing the commonalities in research and prevention regardless of the specific drug, NIAAA entered into a joint project with the Center for Substance Abuse Prevention (CSAP). Thus, The Alcohol and Other Drug Thesaurus: A Guide to Concepts and Terminology in Substance Abuse and Addiction (AOD Thesaurus) was born.

The AOD Thesaurus provides a conceptual map of the multidisciplinary field of AOD research and practice, as well as standard terminology, which, over time, will result in consistent indexing and major improvements in searching and retrieval across many databases. The Thesaurus is already used in indexing and searching both ETOH (reindexed all the way back) and the National Clearinghouse for Alcohol and Drug Information (NCADI) databases. The sponsoring organizations and the Advisory Committee hope that other databases will join as well to promote consistency and ease of use. The Thesaurus is also used by many searchers worldwide to identify useful search terms for any database.

Thesaurus Development and Maintenance

Thesaurus development started with collecting terms and term relationships from many sources: search requests received for ETOH and NCADI databases; document titles and index terms; more than 40 special thesauri; and NIAAA's Reports to Congress on Alcohol and Health and other publications. Major sources used for reference and guidance include the World Health Organization's (WHO's) Lexicon of Alcohol and Drug Terms, developed jointly with NIAAA; NLM's Medical Subject Headings (MESH); the International Classification of Diseases, 9th and 10th Revisions; the DSM-III and draft DSM-IV; the Thesaurus of Psychological Indexing Terms (PsyclNFO); the Thesaurus of ERIC Descriptors; and the Thesaurus of Sociological Indexing Terms (Sociological Abstracts).

The multitude of terms collected from these sources were organized into hierarchies, which brought to the fore many synonyms and near-synonyms. A conceptual analysis process known as semantic factoring further clarified the structure and led to a smaller vocabulary consisting of conceptual building blocks. The resulting structure was thoroughly field-tested through a query formulation and indexing test. Analyzing the results from multiple indexers for important terms missed, different indexers using different terms to express the same idea, terms assigned erroneously, and terms needed but missing from the Thesaurus, the developers identified areas requiring clarification, redundancies between areas, missing cross-references, the need for more or better scope notes, and areas where detail could be reduced. Further refinements were made in this second edition based on indexing and searching experience: Descriptors were added, overly specific descriptors were pruned, the structure was improved, and many scope notes and relationships were added.

The sponsoring organizations are committed to the maintenance of the AOD Thesaurus as an ongoing process driven by user feedback. Users are invited and strongly encouraged to comment on any aspect of the Thesaurus using the enclosed comment form or by e-mail to kmullen@prevline.health.org.

Function and Structure of the Thesaurus

The Thesaurus presents a structured collection of concepts and terms intended to facilitate indexing and retrieval, support research and program planning through conceptual structure and definitions, and improve communication generally through standardized terminology.

The Thesaurus provides guidance to the indexers for request-oriented (or user-centered) indexing. The Thesaurus organizes concepts collected from search requests into an easily grasped hierarchical structure that serves as a framework or checklist in analyzing documents. The logical structure of the Thesaurus communicates user interests to the indexer. The Thesaurus' controlled vocabulary expresses each concept unambiguously through one term, called a descriptor, that is used in indexing and can thus be used with confidence in searching. The Thesaurus leads from a synonym to the descriptor: early intervention leads to JC6.2.4 secondary prevention; chemical abuse, drug abuse, and substance abuse all lead to GC2 AOD abuse; nerve cell and neurocyte both lead to XX2.2 neuron.

The Thesaurus is also very useful for free-text searching (searching based on words in the title or abstract). An exhaustive free-text search must include all terms that might be used to express the searched-for concept. This requires query term expansion: In synonym expansion, expand the query term XX2.2 neuron by adding the synonyms nerve cell and neurocyte; in hierarchic expansion, add narrower terms, such as XX2.2.2.4 dendrite and XX2.2.2.6 axon (with its synonyms, such as nerve fiber and neurite).

"Until further notice, everything is drug-related." This note on a drug counselor's door epitomizes the universal scope of the AOD Thesaurus. The Thesaurus must exercise great conceptual economy if it is to allow for the expression of most concepts and themes while keeping the size manageable. The secret is concept combination; the Thesaurus contains largely elemental concepts from which compound concepts can be formed. For example, alcohol craving is AE6 AOD craving combined with BB2 ethanol; nicotine craving uses BD2 nicotine, etc. Thus any of the many concepts under A AOD use, abuse, and dependence can be combined with any of the substances under B AOD substance or product, obviating the need for enumerating each individual combination. For another example, hepatoma is GG20.26.4.4 carcinoma and GQ10 liver disorder.

The concepts are arranged in a logical hierarchy to orient the user, to help the indexer select the descriptor at the most appropriate level of specificity, and to enable hierarchic query term expansion. An individual hierarchy is often structured into facets, each dealing with a separate aspect. For example, under XX2.2 neuron are the two facets XX2.2.2 neuron structure (which includes the different parts of a neuron) and XX2.2.4 neuron type (including afferent neuron, efferent neuron, motor neuron, etc.). Under JB prevention are the facets JC prevention goals, JF prevention sponsor or setting (such as JF8 community-based prevention and JF10 institution-based prevention, which is further subdivided by type of institution), and JG prevention approach (such as JG12.4 prevention through information dissemination, JG12.8.4 skills building, and JG20.4 prevention through supply reduction). A descriptor (e.g., GQ10.2 alcoholic liver disorder) has as many broader descriptors as are needed to reflect reality (e.g., GQ10 liver disorder and GD4 alcohol related disorder). These polyhierarchical relationships are shown through a rich network of cross-references.

The construction of a hierarchy often profits from new concepts that improve organization and may be useful for searching. For example, JG12.8 prevention through personal development groups affective and interpersonal education, skills building, moral development, and values clarification. HZ4 analytic psychotherapy groups together all psychotherapeutic methods that are based on some form of analysis (as opposed to behavior modification through some form of conditioning).

Terminology Used in the AOD Thesaurus

Use of the Abbreviation AOD

The AOD Thesaurus uses the widely accepted abbreviation AOD for Alcohol and/or Other Drugs. In most descriptors, AOD is used in place of drug or substance; thus, drug dependence becomes AOD dependence, and substance abuse becomes AOD abuse. However, when only other drugs are referred to or when usage dictates, the term drug remains, as in designer drug or drug cartel.

In order to keep descriptors to a manageable length, further abbreviations were introduced as follows:

AOD Alcohol or Other Drugs AODU AOD Use, abuse, and dependence AODD AOD use Disorder AODR AOD Related AODC Causes of AOD use, abuse, and dependence AODE Effects of AOD use, abuse, and dependence These abbreviations appear at the bottom of each page in the Thesaurus listings.

Use of the Term Drug

The term drug is ambiguous; it can refer to AOD, medical drugs, or any chemical substance. In this Thesaurus, drug refers to "other drug," that is, AOD other than alcohol, except in the pharmacology section, where it means any chemical substance including AOD.

In the study of addiction, the terms AOD, drug, and substance are often used interchangeably. As noted above, the Thesaurus uses AOD except where the reference is only to other drugs. It was not practical to provide all possible variations of multiword terms; thus, the Thesaurus includes hazardous AOD use but does not include the synonym hazardous drug use. When an alphabetical index search under drug does not find the looked-for term, try under AOD. The access word substance has only a limited number of entries.

Street terms and slang. Due to profusion, overlap (e.g., dope can refer to marijuana or heroin), and the rapid disappearance of old terms and the creation of new ones, the AOD Thesaurus provides few street terms or slang terms with respect to alcohol and other drugs and their use. (For a good reference see Street Terms: Drugs and the Drug Trade. Office for National Drug Control (ONDCP), Drugs and Crime Clearinghouse. February 1995. 1-800-666-3332, askncjrs@ncjrs.aspensys.com)

Singular versus plural. As a rule, singular is preferred. Exceptions are class descriptors in W Living organisms and Y/Z Chemical substances, where classes are traditionally designated by a plural term (e.g., protists, aldehydes). Other exceptions are expressions that are commonly used in the plural, such as fetal alcohol effects, or that otherwise make more sense or sound more natural in the plural.

Use of hyphens. Hyphens are usually omitted�even where required by normal usage�in order to avoid complications when entering search terms.

Thesaurus Format

The AOD Thesaurus is arranged like a book in three parts: successively detailed tables of contents� the Broad and Detailed Outlines and the Quick Hierarchy following the introduction (Volume 1); a systematically arranged main body of information�the Annotated Hierarchy (Volume 2); and the Alphabetical Index (Volume 3). In addition, the Annotated Alphabetical List (Volume 4) is provided. The facing page shows the relationship between the parts of the Thesaurus and the information provided in each. The figure at the bottom of this page shows an excerpt from the Annotated Alphabetical List. More detailed explanations and sample pages follow.

Orientation and Navigation in the AOD Thesaurus

To get a feel for the organization of the Thesaurus' wide-ranging subject matter, start with the Broad Outline and/or one of the Orientation Maps on pp. viii-x. Then get an increasingly detailed look by perusing sections of interest in the Detailed Outline and the Quick Hierarchy and finally by reviewing the Annotated Hierarchy with its scope notes and cross-references that link all the subjects together.

Navigation in the Thesaurus to find descriptors for indexing and searching can start with a general idea of a subject area or with a specific term. To go from a general idea to a specific concept, the user might follow the systematic stepwise refinement strategy discussed above, or he or she might just scan the tabs in the Annotated Hierarchy and delve directly into it; familiarity with the hierarchy comes with experience. In the Annotated Hierarchy, read the scope note and the cross-references, which may lead to additional or more suitable descriptors. If you have a specific term in mind, you can look it up in the Alphabetical Index and follow the term number given there into the Annotated Hierarchy to see the hierarchical context and the full body of information. Alternatively, you can consult the Annotated Alphabetical List; however, keep in mind two things: The Annotated Alphabetical List does not provide the hierarchical context; you cannot quickly see the scope note for a broader or near-by descriptor. Also, the Annotated Alphabetical List shows a term in only one place, whereas the Alphabetical Index shows a term under each of its constituent words. For example, secondary prevention will appear only under secondary in the Annotated Alphabetical List, whereas in the Alphabetical Index, it will appear under secondary and prevention.

Volume 2: Annotated Hierarchy

The Annotated Hierarchy shows all descriptors in a logical arrangement and provides a considerable amount of information for many of them (for examples, see the facing page and the two following pages). Each descriptor has a term number that identifies its home location in the hierarchy; these numbers allow the user to quickly locate a descriptor in the hierarchy. When a descriptor has two or more broader descriptors (such as GQ10.2 alcoholic liver disorder with the broader descriptors GQ10 liver disorder and GE6 alcohol related disorder), one is selected as the home location. The home location determines the descriptor's term number; in the example, alcoholic liver disorder is listed under GQ10 with the term number GQ10.2. Under the other broader descriptor, GE6, is a narrower term cross-reference to GQ10.2. Thus, a descriptor is never assigned more than one term number (unlike MESH, which assigns multiple term numbers to the same descriptor, one number for each descriptor placement in the hierarchy). Only a subset of descriptors is used in the ETOH database; ETOH descriptors are identified through a subscript "e" after the term number: GQ10.2e.

Term numbers are printed to the left. Descriptors are printed to the right, with the hierarchical level expressed through typography and arrangement as follows:

In cases where the hierarchy is very deep, these typographical rules were adjusted for readability. The hierarchical level can always be seen from the Detailed Outline in Volume 1 or at the beginning of each major section in Volume 2.

To preserve the continuity of the hierarchy, left pages repeat, in italics, the hierarchical chain (starting from level 2) leading to the first descriptor on the page. (The running heads show levels 0 and 1.)

Scope notes (SN) give definitions and explanations of descriptor usage or of the hierarchical structure. Synonymous terms (ST, including quasi-synonyms) further clarify the scope of the descriptor. Broader term (BT) cross-references indicate other places in the hierarchy where the descriptor would logically fit; conversely, narrower term (NT) cross-references indicate additional narrower descriptors that have their home location elsewhere. (To conserve space, cross-references are shown only one level up or down, respectively.) Related term (RT) cross- references point to descriptors that are similar in meaning or that might be useful for combinations. In a cross-reference, a + before the term number means that the descriptor referred to has narrower descriptors that should be considered.

Further Explanation of Term Numbers

The major areas of the hierarchy (level 0) are identified by a capital letter (e.g., J, with gaps for future expansion), and the major subdivisions (level 1 or further down the hierarchy) are identified by a second letter (e.g., JB, JC). Within a major subdivision, descriptors are then identified by a number (e.g., JC2, JC4). Further down the hierarchy, descriptors are numbered the same way, with a dot (.) separating the levels (e.g., JC2.2, JC2.4, or JG12.8.4). To keep term numbers short, two-letter combinations for subdivisions are assigned based on importance; the hierarchical level can vary from 1 to 6. Thus, term numbers do not reflect the hierarchical level of a descriptor. The hierarchical level can always be seen from the Detailed Outline. Term numbers are valid only for navigation in one edition of the Thesaurus; they may change from edition to edition.

Volume 3: Alphabetical Index

The Alphabetical Index is a Key Word Out of Context (KWOC) index that shows a multiword term under each of its constituent words (except for stop words, such as and, of, and for). Thus, SO4.2 alcoholic beverage industry appears under the access words alcoholic, beverage, and industry; see the facing sample page for an illustration of the typography and page layout. (The sample page was constructed to illustrate all features.)

There are many italicized lead-in terms in the Alphabetical Index that will lead the user to a descriptor in the hierarchy where there will be no corresponding synonymous term (ST) under that descriptor. This indicates that the term was considered to be too specific for the Thesaurus at this time and leads to the appropriate broader term. For example, it was decided not to use proper names of tests, such as MAST or the CAGE questionnaire, as descriptors. However, these terms do appear in the Alphabetical Index and lead to their broader heading, in the example HB6.10.24 alcohol use test.

Volume 4: Annotated Alphabetical List

The Annotated Alphabetical List is a list of all the terms in the Thesaurus. Unlike the Alphabetical Index, which shows each term under each of its constituent words, the Annotated Alphabetical List shows each term only once; thus, drug evaluation appears only under drug and not also under evaluation. See the sample column on the facing page for an illustration of the typography and page layout. (The sample page was constructed to illustrate all features.)